Postdoc position with experience in mammalian cell biology, PERFECTION group, Rigshospitalet

We are looking for a Mammalian Cell Biologist who will be responsible for developing human lung cell cultures as in vitro models for investigations of bacterial infections.     

The position is affiliated with the main hospital in Denmark, Rigshospitalet, Copenhagen. The experimental activities are placed at The Technical University of Denmark (DTU, Biosustain).

The proposed start date of this position is February 1, 2024, or as soon as possible. The position will be for 3 years.

The group consists of a highly motivated team of engineers, biologists, clinicians, and students. Important focus points of the project are to elucidate host/microbe interactions and responses to fluctuating environmental conditions, within the lung, using a newly developed miniature organ infection model (‘organoids’) as well as in air liquid interface cell cultures (‘ALI’) of human lung. We perform multi-omics and bioprocess data analysis, and we design strategies for identifying and testing biomarkers for improved clinical diagnostics as well as the action of new and old types of antibiotics.

The research in the PERFECTION group is headed by Professor Helle Krogh Johansen, Rigshospitalet and Professor Søren Molin, DTU.

Responsibilities and tasks

You will integrate your expertise in cell biology with the existing expertise in microbiology, infection biology and molecular biology to develop our translational medicine project in direction of improved diagnostics and novel therapeutic strategies for infectious lung diseases. We expect you to take part in the continued development and optimization of our experimental model systems, to take on supervision of students, and to initiate new approaches relevant for starting new research projects. You will also be responsible for writing scientific papers and grant applications.

Qualifications
Candidates should have a PhD degree in the field of mammalian cell biology or similar. We are looking for a candidate with a detailed theoretical knowledge in cell biology and molecular biology. Experimental experience in cell biology and mammalian cell culture is essential, including compliance with the highest laboratory standards. Moreover, experience with one or more of the following is preferred:

• microbial infections
• standard cell/molecular biology techniques: immunostaining, PCR, RNA and protein expression, flow cytometry
• advanced omics techniques: dual RNA-seq, dual proteomics
• microscopy and image analysis

In addition, you must

• enjoy working with complex biological systems
• thrive in teamwork with a focus on process as well as outcome
• believe in dialogue and feedback as the best foundation for sound decision-making

What we offer in return
We offer an interesting and challenging job in an international cross-disciplinary atmosphere with the focus on research, education, innovation, and translation of basic science results to clinical applications for the benefit of patients. We offer a great flexibility in the position, spanning several hospitals and DTU departments.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

Further information
Further information may be obtained from Professor Helle Krogh Johansen, telephone +45 3122 8406, mail hkj@biosustain.dtu.dk

Application procedure 
Please submit your online application no later than December 15, 2023.

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English as one PDF file. The file must include:

• Application (cover letter)
• CV (including details, under appropriate headings, starting with the most recent)
• Diploma (Bachelor/Master/PhD)
• List of publications 

Please note, that applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. 
The Centre of Diagnostic Investigation comprises a collection of highly specialized departments: Diagnostic radiology, clinical biochemistry, pathology, clinical immunology, clinical physiology/nuclearmedicine and PET, clinical microbiology, clinical genetics, center of genomic medicine. 

The center has a staff of 1.800 and an annual turnover of 1.1 billion kroner. The center produces annually 10 mill. laboratory analyses and performs 650.000 image diagnostics based on 1 mill. contacts with patients and donors.

The core task is high-level research, strong educational environments, customized diagnostics and patient treatment. 35 professors and other researchers provides annually more than 700 scientific articles in international reputable journals.

• Fakta

• Arbejdssted
  Rigshospitalet, Blegdamsvej
• Kontaktperson
  Helle Krogh Johansen
• Adresse
  Blegdamsvej 9, 2100 København Ø
• Stillingstype
  Molekylærbiolog
• Ansættelsesform
  Tidsbegrænset periode
• Ugentlig arbejdstid
  Fuld tid
• Ansættelsens start
  01-02-2024
• Regionens jobnr.
  252754
• Quick-nr.
  456188
• Indrykningsdato
  14-11-2023
• Ansøgningsfrist
  15-12-2023 (udløbet)