Postdoc in neuroendocrine histology focusing on mapping glucagon receptor expression

Are you passionate about the brain and histological research methods? Do you want to make a meaningful contribution to translational science in metabolism and metabolic diseases?

We are looking for a motivated postdoc to join Nicolai J. Wewer Albrechtsen’s research group at the Department of Clinical Biochemistry, Bispebjerg Hospital. We are currently a team of 3 PhD students, 2 research assistants, 4 postdocs, 1 chemist, 3 bioanalytical technicians, 3 students. This is a 1-year position starting April 1, 2025 (or as agreed), with the potential for extension for two years.

We research the hormone glucagon, which is essential for our metabolism. Our latest findings suggest that glucagon may also play a role in the development of diseases such as diabetes and dementia. In this project, you will investigate glucagon’s potential role in brain metabolism and function by mapping the localization of its receptor in brain tissue from mice and humans.

Key Responsibilities

• Lead and conduct studies to map glucagon receptor expression in mice and human brain tissue.
• Apply and optimize histological techniques, including autofluorescent ligands, in situ hybridization, and immunohistochemistry.
• Independently drive research projects and contribute to team collaborations.
• Engage in cross-disciplinary collaborations within the department and with external partners.

What We Offer

• A chance to contribute to exciting research within metabolism and metabolic diseases.
• A dynamic, interdisciplinary team of physicians, students, bioanalysts, and researchers.
• Opportunities for project management and supervision of technical staff and students.
• Participation in scientific meetings and collaborative studies.

What We Expect

• A relevant master’s and PhD degree
• Hands-on experience with the following techniques:
  • Sectioning (cryosectioning, paraffin embedding), staining, and slide preparation
  • Fluorescent labeling and imaging
  • In situ hybridization (RNAscope)
  • Immunohistochemistry
  • Confocal and fluorescence microscopy
  • Software for image analysis
• Additional experience with the following is an advantage:
  • Working with mice, perfusion fixation, and tissue collection
• Strong communication skills

Part of the studies will be performed in collaboration with https://cfim.ku.dk/

About the Department

The Department of Clinical Biochemistry provides 24/7 service to Bispebjerg and Frederiksberg Hospitals, as well as general practitioners, specialists, psychiatry, and private hospitals. We process over 10.5 million tests annually and are based in state-of-the-art facilities since 2020. With 140 dedicated staff members, including 80 bioanalysts, we thrive on teamwork, knowledge-sharing, and innovation.

For more about the department, visit:

Bispebjerg Hospital Clinical Biochemistry

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Contact & Application

For further information, please contact:

Marie Winther Achu, Postdoc – marie.winther.achu@regionh.dk

Camilla Bjørnbak Holst, Specialist Registrar – camilla.bjoernbak.holst.01@regionh.dk 

Nicolai J. Wewer Albrechtsen, Professor, Chief Physician at Department of Clinical Biochemistry and Leader of Center for Translational Research – nicolai.albrechtsen@regionh.dk

Working hours: Full-time (37 hours/week) unless otherwise agreed.

Salary and terms: In accordance with the applicable collective agreement.

Application deadline 28th of February 2025.

We will do interview continuously during the application period.

• Fakta

• Arbejdssted
  Bispebjerg og Frederiksberg Hospital
• Kontaktperson
  Nicolai Albrechtsen
  nicolai.albrechtsen@regionh.dk
• Adresse
  Bispebjerg Bakke 23, 2400 København NV
• Stillingstype
  Biokemiker
• Ansættelsesform
  Tidsbegrænset periode
• Ugentlig arbejdstid
  Fuld tid
• Ansættelsens start
  01-04-2025
• Regionens jobnr.
  260962
• Quick-nr.
  472977
• Indrykningsdato
  07-02-2025
• Ansøgningsfrist
  28-02-2025